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R&D Systems elisa kit
Elisa Kit, supplied by R&D Systems, used in various techniques. Bioz Stars score: 93/100, based on 20 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/human+corin+quantikine+elisa+kit/Human+Corin+Quantikine+ELISA+Kit/pmc12403269-104-17-20
Average 93 stars, based on 20 article reviews

elisa kit - by Bioz Stars, 2026-10

93/100 stars

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Enzyme-linked Immunosorbent Assay:

Article Title: Regulated Inositol‐Requiring Protein 1‐Dependent Decay as a Mechanism of Corin RNA and Protein Deficiency in Advanced Human Systolic Heart Failure
Article Snippet: .. Human corin protein was measured in left ventricular lysates using the Human Corin Quantikine ELISA Kit (R&D Systems, Minneapolis, MN). ..

Article Title: Increased levels of soluble corin in pre-eclampsia and fetal growth restriction.
Article Snippet: Atrial natriuretic peptide is biologically activated by the atrial natriuretic peptide-converting enzyme, corin, and has an important role in regulating blood pressure.. We detected elevated serum corin levels in women with pre-eclampsia.. Interestingly, the serum corin levels were also found to be elevated in pregnancies with a related disorder, unexplained fetal growth restriction (FGR) without hypertension, suggesting that this phenomenon is not simply a response to maternal hypertension.

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Effects of CB2R ligands on inhibition of cell migration and VEGFA secretion. A ) Scratch assay evaluated on HGC27-S/R and AGS treated with 1 and 6 µM AM630 and 1 and 10 µM CC48 , Fi9 , ASF151 and 1 . Cells were microscopically analyzed at the time of scratching (T0) and after 24 h (T1). The relative migration rate was calculated by placing the percentage migration of control cells at time T1 equal to 1 and comparing the percentage migration of cells after each drug treatment with this value. The experiments were performed in triples and the average SD values were plotted in the relative graph. * p < 0,05; ** p < 0,01; B ) Representative western blotting analyses performed in HGC27- S/R and AGS cells regarding the expression of P-βcatenin/βcatenin, vimentin and P-cofillin/cofillin. Actin was used as a normalization of the protein extracts; C ) Effects of CB2R ligands on VEGFA/VEGFC secretion. The ELISA assay was assessed on HGC27-S/R and AGS treated with 1 and 6 µM AM630 and 1 and 10 µM CC48 , Fi9 , ASF151 and 1 . The concentration of VEGFA was determined in the medium and normalized for the cell number. The values ± SD, obtained from three independent experiments expressed as pg/mL were shown in the relative graphs.** p < 0,01; *** p < 0,001

Journal: Journal of Experimental & Clinical Cancer Research : CR

Article Title: CC48 a new CB2R agonist/FAAH inhibitor dual drug blocks gastric cancer progression and overcomes paclitaxel resistance

doi: 10.1186/s13046-025-03476-7

Figure Lengend Snippet: Effects of CB2R ligands on inhibition of cell migration and VEGFA secretion. A ) Scratch assay evaluated on HGC27-S/R and AGS treated with 1 and 6 µM AM630 and 1 and 10 µM CC48 , Fi9 , ASF151 and 1 . Cells were microscopically analyzed at the time of scratching (T0) and after 24 h (T1). The relative migration rate was calculated by placing the percentage migration of control cells at time T1 equal to 1 and comparing the percentage migration of cells after each drug treatment with this value. The experiments were performed in triples and the average SD values were plotted in the relative graph. * p < 0,05; ** p < 0,01; B ) Representative western blotting analyses performed in HGC27- S/R and AGS cells regarding the expression of P-βcatenin/βcatenin, vimentin and P-cofillin/cofillin. Actin was used as a normalization of the protein extracts; C ) Effects of CB2R ligands on VEGFA/VEGFC secretion. The ELISA assay was assessed on HGC27-S/R and AGS treated with 1 and 6 µM AM630 and 1 and 10 µM CC48 , Fi9 , ASF151 and 1 . The concentration of VEGFA was determined in the medium and normalized for the cell number. The values ± SD, obtained from three independent experiments expressed as pg/mL were shown in the relative graphs.** p < 0,01; *** p < 0,001

Article Snippet: The amount of VEGFA secreted in the culture medium by HGC27-S/R and AGS treated cells was measured using a highly sensitive Enzyme-Linked Immunosorbent Assay (ELISA), Quantikine Kit ELISA (R&D Systems, Minneapolis, MN, USA), according to the manufacturer’s instructions.

Techniques: Inhibition, Migration, Wound Healing Assay, Control, Western Blot, Expressing, Enzyme-linked Immunosorbent Assay, Concentration Assay

Leveraging the Gusu cohort, a 1‐sample Mendelian randomization study was designed to test the causal relationship between corin and stroke, with serum corin as the E, SNPs at the coding gene of corin as the IV, and stroke as the O. Calculated GRS was also considered as the IV. GRS indicates genetic risk score; E, exposure, IV, instrumental variable; O, outcome; and SNP, single‐nucleotide polymorphism.

Journal: Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease

Article Title: Association Between Genetically Determined Serum Corin and the Risk of Stroke in Chinese Adults: A Mendelian Randomization Study

doi: 10.1161/JAHA.124.035858

Figure Lengend Snippet: Leveraging the Gusu cohort, a 1‐sample Mendelian randomization study was designed to test the causal relationship between corin and stroke, with serum corin as the E, SNPs at the coding gene of corin as the IV, and stroke as the O. Calculated GRS was also considered as the IV. GRS indicates genetic risk score; E, exposure, IV, instrumental variable; O, outcome; and SNP, single‐nucleotide polymorphism.

Article Snippet: We used a quantikine human corin immunoassay (R&D Systems, Inc, Minneapolis, MN; Catalog: DCRN00;) to test soluble corin levels in serum.

Techniques:

The Associations Between CORIN Gene SNPs and Serum Corin Levels in the Gusu Cohort

Journal: Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease

Article Title: Association Between Genetically Determined Serum Corin and the Risk of Stroke in Chinese Adults: A Mendelian Randomization Study

doi: 10.1161/JAHA.124.035858

Figure Lengend Snippet: The Associations Between CORIN Gene SNPs and Serum Corin Levels in the Gusu Cohort

Article Snippet: We used a quantikine human corin immunoassay (R&D Systems, Inc, Minneapolis, MN; Catalog: DCRN00;) to test soluble corin levels in serum.

Techniques:

The Association Between CORIN Gene–Related GRS and the Risk of Stroke in the Gusu Cohort

Journal: Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease

Article Title: Association Between Genetically Determined Serum Corin and the Risk of Stroke in Chinese Adults: A Mendelian Randomization Study

doi: 10.1161/JAHA.124.035858

Figure Lengend Snippet: The Association Between CORIN Gene–Related GRS and the Risk of Stroke in the Gusu Cohort

Article Snippet: We used a quantikine human corin immunoassay (R&D Systems, Inc, Minneapolis, MN; Catalog: DCRN00;) to test soluble corin levels in serum.

Techniques:

Estimates for the Causal Association Between Corin and Stroke From 2‐Stage Least‐Squares MR Analysis

Journal: Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease

Article Title: Association Between Genetically Determined Serum Corin and the Risk of Stroke in Chinese Adults: A Mendelian Randomization Study

doi: 10.1161/JAHA.124.035858

Figure Lengend Snippet: Estimates for the Causal Association Between Corin and Stroke From 2‐Stage Least‐Squares MR Analysis

Article Snippet: We used a quantikine human corin immunoassay (R&D Systems, Inc, Minneapolis, MN; Catalog: DCRN00;) to test soluble corin levels in serum.

Techniques:

The fixed‐effect IVW analysis is based on the unadjusted, age and sex‐adjusted, and multivariate‐adjusted SNP‐corin and SNP‐stroke associations. Abscissa values indicate the SD change in log 2 ‐transformed corin per allele. Ordinate values indicate the logarithm of the HR of stroke per allele. HR indicates hazard ratio; IVW, inverse variance–weighted; MR, Mendelian randomization; and SNPs, single‐nucleotide polymorphisms.

Journal: Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease

Article Title: Association Between Genetically Determined Serum Corin and the Risk of Stroke in Chinese Adults: A Mendelian Randomization Study

doi: 10.1161/JAHA.124.035858

Figure Lengend Snippet: The fixed‐effect IVW analysis is based on the unadjusted, age and sex‐adjusted, and multivariate‐adjusted SNP‐corin and SNP‐stroke associations. Abscissa values indicate the SD change in log 2 ‐transformed corin per allele. Ordinate values indicate the logarithm of the HR of stroke per allele. HR indicates hazard ratio; IVW, inverse variance–weighted; MR, Mendelian randomization; and SNPs, single‐nucleotide polymorphisms.

Article Snippet: We used a quantikine human corin immunoassay (R&D Systems, Inc, Minneapolis, MN; Catalog: DCRN00;) to test soluble corin levels in serum.

Techniques: Transformation Assay

Estimates for the Causal Association Between Corin and Stroke From 2‐Sample MR Analyses

Journal: Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease

Article Title: Association Between Genetically Determined Serum Corin and the Risk of Stroke in Chinese Adults: A Mendelian Randomization Study

doi: 10.1161/JAHA.124.035858

Figure Lengend Snippet: Estimates for the Causal Association Between Corin and Stroke From 2‐Sample MR Analyses

Article Snippet: We used a quantikine human corin immunoassay (R&D Systems, Inc, Minneapolis, MN; Catalog: DCRN00;) to test soluble corin levels in serum.

Techniques:

The HRs indicate the pooled estimates from the fixed‐effect IVW analysis based on the unadjusted, age‐ and sex‐adjusted, and multivariate‐adjusted SNP‐corin and SNP‐stroke associations, where each SNP was iteratively removed from the instruments. HR indicates hazard ratio; IVW, inverse variance–weighted; and SNPs, single‐nucleotide polymorphisms.

Journal: Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease

Article Title: Association Between Genetically Determined Serum Corin and the Risk of Stroke in Chinese Adults: A Mendelian Randomization Study

doi: 10.1161/JAHA.124.035858

Figure Lengend Snippet: The HRs indicate the pooled estimates from the fixed‐effect IVW analysis based on the unadjusted, age‐ and sex‐adjusted, and multivariate‐adjusted SNP‐corin and SNP‐stroke associations, where each SNP was iteratively removed from the instruments. HR indicates hazard ratio; IVW, inverse variance–weighted; and SNPs, single‐nucleotide polymorphisms.

Article Snippet: We used a quantikine human corin immunoassay (R&D Systems, Inc, Minneapolis, MN; Catalog: DCRN00;) to test soluble corin levels in serum.

Techniques:

The ORs indicate the pooled estimates from the fixed‐effect IVW analysis based on the multivariate‐adjusted SNP‐corin associations in our original data and summarized SNP‐stroke associations in external data. CES indicates cardioembolic stroke; IS, ischemic stroke; IVW, inverse variance–weighted; LAS, large artery stroke; OR, odds ratio; SNP, single‐nucleotide polymorphism; and SVS, small‐vessel stroke.

Journal: Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease

Article Title: Association Between Genetically Determined Serum Corin and the Risk of Stroke in Chinese Adults: A Mendelian Randomization Study

doi: 10.1161/JAHA.124.035858

Figure Lengend Snippet: The ORs indicate the pooled estimates from the fixed‐effect IVW analysis based on the multivariate‐adjusted SNP‐corin associations in our original data and summarized SNP‐stroke associations in external data. CES indicates cardioembolic stroke; IS, ischemic stroke; IVW, inverse variance–weighted; LAS, large artery stroke; OR, odds ratio; SNP, single‐nucleotide polymorphism; and SVS, small‐vessel stroke.

Article Snippet: We used a quantikine human corin immunoassay (R&D Systems, Inc, Minneapolis, MN; Catalog: DCRN00;) to test soluble corin levels in serum.

Techniques:

Figure 2. Pre- and postprocedural plasma corin levels in patients treated with catheter ablation for atrial fibrillation. A, Total group; (B) subgroup analysis of atrial fibrillation type; (C) subgroup analysis of sex. The box diagram represents the 5% to 95% range of values. **P<0.0001.

Journal: Journal of the American Heart Association

Article Title: Association of Preablation Plasma Corin Levels With Atrial Fibrillation Recurrence After Catheter Ablation: A Prospective Observational Study

doi: 10.1161/jaha.123.031928

Figure Lengend Snippet: Figure 2. Pre- and postprocedural plasma corin levels in patients treated with catheter ablation for atrial fibrillation. A, Total group; (B) subgroup analysis of atrial fibrillation type; (C) subgroup analysis of sex. The box diagram represents the 5% to 95% range of values. **P<0.0001.

Article Snippet: Plasma corin concentrations were measured with human corin Quantikine ELISA kits (Catalog: DCRN00, R&D Systems, Minneapolis, MN).21,26,27

Techniques: Clinical Proteomics

Figure 3. The association between corin levels before and after ablation. A, Total group; (B) nonrecurrence group; (C) recurrence group. The shaded region indicates the 95% CIs of Spearman r value.

Journal: Journal of the American Heart Association

Article Title: Association of Preablation Plasma Corin Levels With Atrial Fibrillation Recurrence After Catheter Ablation: A Prospective Observational Study

doi: 10.1161/jaha.123.031928

Figure Lengend Snippet: Figure 3. The association between corin levels before and after ablation. A, Total group; (B) nonrecurrence group; (C) recurrence group. The shaded region indicates the 95% CIs of Spearman r value.

Article Snippet: Plasma corin concentrations were measured with human corin Quantikine ELISA kits (Catalog: DCRN00, R&D Systems, Minneapolis, MN).21,26,27

Techniques:

Figure 5. Kaplan–Meier curves showing recurrent atrial fibrillation at 1 year after catheter ablation for different corin levels. A through E, Corin levels before ablation in total, PaAF, PeAF, male and female groups; F through J, corin levels after ablation in total, PaAF, PeAF, male and female. HR indicates hazard ratio; PaAF, paroxysmal atrial fibrillation; and PeAF, persistent atrial fibrillation.

Journal: Journal of the American Heart Association

Article Title: Association of Preablation Plasma Corin Levels With Atrial Fibrillation Recurrence After Catheter Ablation: A Prospective Observational Study

doi: 10.1161/jaha.123.031928

Figure Lengend Snippet: Figure 5. Kaplan–Meier curves showing recurrent atrial fibrillation at 1 year after catheter ablation for different corin levels. A through E, Corin levels before ablation in total, PaAF, PeAF, male and female groups; F through J, corin levels after ablation in total, PaAF, PeAF, male and female. HR indicates hazard ratio; PaAF, paroxysmal atrial fibrillation; and PeAF, persistent atrial fibrillation.

Article Snippet: Plasma corin concentrations were measured with human corin Quantikine ELISA kits (Catalog: DCRN00, R&D Systems, Minneapolis, MN).21,26,27

Techniques:

Figure 4. Plasma corin threshold of best predictive value for recurrent atrial fibrillation at 1 year after catheter ablation. A, Total group; (B) subgroup analysis of atrial fibrillation type; (C) subgroup analysis of sex. AUC indicates area under the curve; PaAF, paroxysmal atrial fibrillation; and PeAF, persistent atrial fibrillation.

Journal: Journal of the American Heart Association

Article Title: Association of Preablation Plasma Corin Levels With Atrial Fibrillation Recurrence After Catheter Ablation: A Prospective Observational Study

doi: 10.1161/jaha.123.031928

Figure Lengend Snippet: Figure 4. Plasma corin threshold of best predictive value for recurrent atrial fibrillation at 1 year after catheter ablation. A, Total group; (B) subgroup analysis of atrial fibrillation type; (C) subgroup analysis of sex. AUC indicates area under the curve; PaAF, paroxysmal atrial fibrillation; and PeAF, persistent atrial fibrillation.

Article Snippet: Plasma corin concentrations were measured with human corin Quantikine ELISA kits (Catalog: DCRN00, R&D Systems, Minneapolis, MN).21,26,27

Techniques: Clinical Proteomics

Figure 6. Hazard ratios with 95% CIs for 1 SD increase in corin concentration of recurrent atrial fibrillation at 1 year after catheter ablation. A, Crude model; (B) adjusted model (adjusted for age, sex, body mass index, triglyceride, high-density lipoprotein cholesterol, antiarrhythmic drugs, β-blockers and corin levels before or after catheter ablation). HR indicates hazard ratio; PaAF, paroxysmal atrial fibrillation; and PeAF, persistent atrial fibrillation. **P<0.0001.

Journal: Journal of the American Heart Association

Article Title: Association of Preablation Plasma Corin Levels With Atrial Fibrillation Recurrence After Catheter Ablation: A Prospective Observational Study

doi: 10.1161/jaha.123.031928

Figure Lengend Snippet: Figure 6. Hazard ratios with 95% CIs for 1 SD increase in corin concentration of recurrent atrial fibrillation at 1 year after catheter ablation. A, Crude model; (B) adjusted model (adjusted for age, sex, body mass index, triglyceride, high-density lipoprotein cholesterol, antiarrhythmic drugs, β-blockers and corin levels before or after catheter ablation). HR indicates hazard ratio; PaAF, paroxysmal atrial fibrillation; and PeAF, persistent atrial fibrillation. **P<0.0001.

Article Snippet: Plasma corin concentrations were measured with human corin Quantikine ELISA kits (Catalog: DCRN00, R&D Systems, Minneapolis, MN).21,26,27

Techniques: Concentration Assay

Figure 7. Predictors of recurrent atrial fibrillation at 1 year after catheter ablation in adjusted models. Adjusted for age, sex, body mass index, triglyceride, high-density lipoprotein cholesterol, antiarrhythmic drugs, β-blockers, and corin levels before or after catheter ablation. The continuous variables were log-transformed and 1 SD was used for odds ratio calculation. AADs indicates antiarrhythmic drugs; AF, atrial fibrillation; BMI, body mass index; HDL-C, high-density lipoprotein cholesterol; OR, odds ratio; PaAF, paroxysmal atrial fibrillation; PeAF, persistent atrial fibrillation; and TG, triglyceride. **P<0.0001.

Journal: Journal of the American Heart Association

Article Title: Association of Preablation Plasma Corin Levels With Atrial Fibrillation Recurrence After Catheter Ablation: A Prospective Observational Study

doi: 10.1161/jaha.123.031928

Figure Lengend Snippet: Figure 7. Predictors of recurrent atrial fibrillation at 1 year after catheter ablation in adjusted models. Adjusted for age, sex, body mass index, triglyceride, high-density lipoprotein cholesterol, antiarrhythmic drugs, β-blockers, and corin levels before or after catheter ablation. The continuous variables were log-transformed and 1 SD was used for odds ratio calculation. AADs indicates antiarrhythmic drugs; AF, atrial fibrillation; BMI, body mass index; HDL-C, high-density lipoprotein cholesterol; OR, odds ratio; PaAF, paroxysmal atrial fibrillation; PeAF, persistent atrial fibrillation; and TG, triglyceride. **P<0.0001.

Article Snippet: Plasma corin concentrations were measured with human corin Quantikine ELISA kits (Catalog: DCRN00, R&D Systems, Minneapolis, MN).21,26,27

Techniques: Transformation Assay

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